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Introduction - Worksheet Questions-Anatomy And Physiology
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The assignments contain the answers to the question that determine the observation of the results of the glucose tolerance tests. It also describes the regulation of the homeostasis mechanism of glucose that gives stimulus to the high glucose levels in the blood.
1.a Glucose tolerance test results for Maria and Laura
The glucose tolerance test result for Maria and Laura is examined after 30, 60, 90 and 120 minutes. It is observed from the result that with the increase in time blood glucose level of Laura is found to be more than Maria at different times. It means that Laura has a higher blood sugar level than Maria.
Clinical Implication of the results
It can be determined from the result that their blood sugar level Laura when observed from 30 minutes to 120 minutes shows a level ranging from 9.4 to 16.7 mmol/l. A blood sugar level ranging between 7.8 and 11 mmol/l is considered to be impaired glucose tolerance which is also known as pre-diabetes whereas if the level is higher than 11.1 mmol/l indicated that the person is suffering from diabetes (Kuo et al. 2021). So, Laura is either at risk of having diabetes but there is no such risk observed in Maria.
1.bThe homeostatic mechanism for the regulation of glucose
The blood sugar level of the pancreas is mainly ranging from 4-6 mM with the help of certain hormones such as Insulin and Glucagon. When blood glucose level increases, the change is detected by the hormonal system and the release of insulin occurs from the pancreas which maintains the glucose level in the blood.
Its maintenance is generally accomplished by the balanced and opposing actions of the above two hormones (Brown, Scarlett & Schwartz, 2019). Thus, this results in the regulation of the homeostasis of glucose.
It can be concluded from the above results that Laura has a high blood sugar level than Maria and is at a high risk of diabetes or either having diabetes. The regulation of glucose homeostasis to maintain high blood glucose levels is maintained by hormones.
- Bio.libretexts.org, 2019, Feedback Loops: Glucose and Glucagon, Retrieved from: https://bio.libretexts.org/Learning_Objects/Worksheets/Book%3A_The_Biology_Corner_(Worksheets)/Anatomy_Worksheets/Feedback_Loops%3A_Glucose_and_Glucagon, Retrieved on: 6th October, 2022
- Brown, J. M., Scarlett, J. M., & Schwartz, M. W. (2019). Rethinking the role of the brain in glucose homeostasis and diabetes pathogenesis. The Journal of Clinical Investigation, 129(8), 3035-3037. https://www.jci.org/articles/view/130904/pdf
- Kuo, F. Y., Cheng, K. C., Li, Y., & Cheng, J. T. (2021). Oral glucose tolerance test in diabetes, the old method revisited. World Journal of Diabetes, 12(6), 786. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192259/